Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674236 | 0.87 | EPHA2 (0.43) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL26105464 | 0.79 | USP2 (0.43) | GPR119USP2SMN1; SMN2RORCKDM4E | |
| SCHEMBL26104643 | 0.79 | USP2 (0.43) | GPR119USP2SMN1; SMN2RORCKDM4E | |
| SCHEMBL23326749 | 0.79 | USP2 (0.39) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL29861237 | 0.79 | USP2 (0.39) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL23326772 | 0.76 | USP2 (0.40) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL29861418 | 0.76 | USP2 (0.40) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL28655023 | 0.76 | NR1H2 (0.39) | GPR119USP2SMN1; SMN2RORCNPC1 | |
| SCHEMBL31197159 | 0.75 | USP2 (0.57) | USP30GPR119USP2SMN1; SMN2RORC | |
| SCHEMBL27037430 | 0.75 | USP2 (0.57) | USP30GPR119USP2SMN1; SMN2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727758-A | Bicyclic heterocyclic compounds and use thereof | 锐新医药公司 | 2021-11-30 | — | — | CN | disclosed |