Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326749 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL29861418 | 0.87 | USP2 (0.40) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL23326772 | 0.87 | USP2 (0.40) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL23326682 | 0.83 | GPR119 (0.38) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL23326681 | 0.83 | GPR119 (0.38) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL28654933 | 0.79 | USP30 (0.40) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL23326529 | 0.78 | GPR119 (0.36) | USP2SMN1; SMN2GPR119USP30 | |
| SCHEMBL23326528 | 0.78 | GPR119 (0.36) | USP2SMN1; SMN2GPR119USP30 | |
| SCHEMBL23326526 | 0.78 | GPR119 (0.36) | USP2SMN1; SMN2GPR119USP30 | |
| SCHEMBL23326527 | 0.78 | GPR119 (0.36) | USP2SMN1; SMN2GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425742-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |