Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654933 | 0.87 | USP30 (0.40) | EPHA2USP2SMN1; SMN2USP30RORC | |
| SCHEMBL29861418 | 0.80 | USP2 (0.40) | EPHA2USP2SMN1; SMN2USP30RORC | |
| SCHEMBL23326772 | 0.80 | USP2 (0.40) | EPHA2USP2SMN1; SMN2USP30RORC | |
| SCHEMBL26105464 | 0.80 | USP2 (0.43) | EPHA2USP2SMN1; SMN2RORCGPR119 | |
| SCHEMBL26104643 | 0.80 | USP2 (0.43) | EPHA2USP2SMN1; SMN2RORCGPR119 | |
| SCHEMBL1552614 | 0.78 | EPHA2 (0.51) | EPHA2USP2SMN1; SMN2USP30GPR119 | |
| SCHEMBL1552612 | 0.78 | EPHA2 (0.51) | EPHA2USP2SMN1; SMN2USP30GPR119 | |
| SCHEMBL28659302 | 0.77 | EPHA2 (0.44) | EPHA2USP2SMN1; SMN2USP30RORC | |
| SCHEMBL29861237 | 0.76 | USP2 (0.39) | USP2SMN1; SMN2USP30RORCGPR119 | |
| SCHEMBL23326749 | 0.76 | USP2 (0.39) | USP2SMN1; SMN2USP30RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727758-A | Bicyclic heterocyclic compounds and use thereof | 锐新医药公司 | 2021-11-30 | — | — | CN | disclosed |