SCHEMBL28655176

SCHEMBL28655176

Cc1cc(C)c(C(=O)P(=O)(CCP(=O)(O)O)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 4/20 0.40
PGK2 P07205 4/20 0.40
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAS1R3 Q7RTX0 4/20 0.36
TAS1R1 Q7RTX1 4/20 0.36
TAS1R2 Q8TE23 4/20 0.36
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1035616 0.85 KMT2A (0.40) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL5160037 0.84 KMT2A (0.39) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL1029138 0.84 KMT2A (0.39) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL6470374 0.84 KMT2A (0.42) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL1032887 0.82 KMT2A (0.38) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL12956433 0.82 LMNA (0.39) PGK1PGK2KMT2AMEN1LMNA
SCHEMBL15637216 0.81 NPSR1 (0.39) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL2497195 0.81 HPGD (0.41) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL1033301 0.80 PPARD (0.42) KMT2AMEN1LMNAHPGDSMN1; SMN2
SCHEMBL2499305 0.79 HPGD (0.45) PGK1PGK2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383874-B Process for preparing acylphosphanes 瑞士联邦苏黎世技术大学 2021-10-08 CN disclosed