Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28656183 | 0.83 | MAPT (0.61) | NPC1RAB9AABL1KDM1AMAOA | |
| SCHEMBL23553571 | 0.75 | MAPT (0.74) | NPC1RAB9AABL1MAPTGLA | |
| SCHEMBL23553978 | 0.73 | CFTR (0.77) | ABL1KDM1AMAOAMAPTGLA | |
| SCHEMBL23691364 | 0.73 | MAPT (0.60) | NPC1RAB9AABL1KDM1AMAOA | |
| SCHEMBL17144293 | 0.72 | MAOB (0.73) | MAOA | |
| SCHEMBL10815310 | 0.72 | ABL1 (0.80) | NPC1RAB9AABL1KDM1AMAOA | |
| SCHEMBL29419343 | 0.72 | MAPT (0.69) | NPC1RAB9AABL1KDM1AMAOA | |
| SCHEMBL18387738 | 0.72 | MAPT (0.69) | NPC1RAB9AABL1KDM1AMAOA | |
| SCHEMBL10924820 | 0.72 | ABL1 (0.80) | ABL1KDM1AMAOAMAPTGLA | |
| SCHEMBL1821159 | 0.72 | RAB9A (1.00) | NPC1RAB9AMAOAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794125-B | NAT10 modulators for the treatment or prevention of laminopathies, aging and cancer | 剑桥企业有限公司 | 2021-11-23 | — | — | CN | claimed |