Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655555 | 0.86 | AR (0.42) | KDM4E | |
| SCHEMBL30774158 | 0.79 | ALDH1A1 (0.37) | KDM4E | |
| SCHEMBL24373483 | 0.79 | ALDH1A1 (0.37) | KDM4E | |
| SCHEMBL28669735 | 0.75 | CXCR2 (0.37) | — | |
| SCHEMBL29479071 | 0.75 | KDM4E (0.51) | KDM4E | |
| SCHEMBL24373525 | 0.75 | KDM4E (0.51) | KDM4E | |
| SCHEMBL28673314 | 0.70 | ALDH1A1 (0.34) | KDM4E | |
| SCHEMBL30950256 | 0.70 | ALDH1A1 (0.34) | KDM4E | |
| SCHEMBL24373521 | 0.68 | KDM4E (0.43) | KDM4E | |
| SCHEMBL25301152 | 0.68 | PSMB8 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |