Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | DHPS | P49366 | 2/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655531 | 0.86 | KDM4E (0.32) | KDM4E | |
| SCHEMBL24373525 | 0.85 | KDM4E (0.51) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL29479071 | 0.85 | KDM4E (0.51) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL30774158 | 0.79 | ALDH1A1 (0.37) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL24373483 | 0.79 | ALDH1A1 (0.37) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL24010308 | 0.74 | KDM4E (0.60) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL30288398 | 0.74 | KDM4E (0.60) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL24373521 | 0.73 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL30950256 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL28673314 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | disclosed |