Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501539 | 0.89 | NR1H4 (0.73) | KCNK9NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7302565 | 0.89 | KCNK9 (0.76) | KCNK9NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4250752 | 0.86 | KCNK9 (0.81) | KCNK9NPC1RAB9ANR1H4HDAC3 | |
| SCHEMBL2345780 | 0.86 | EPHX1 (0.68) | KCNK9NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8218803 | 0.85 | NR1H4 (0.63) | NPC1RAB9AMEN1KMT2ANR1H4 | |
| SCHEMBL7303163 | 0.84 | HDAC3 (0.86) | NPC1RAB9AMEN1KMT2ANR1H4 | |
| SCHEMBL3404122 | 0.84 | NR1H4 (0.60) | NPC1RAB9AMEN1KMT2ANR1H4 | |
| SCHEMBL907217 | 0.84 | EPHX2 (0.60) | NPC1RAB9AMEN1KMT2ANR1H4 | |
| SCHEMBL12044572 | 0.83 | PTPN1 (0.70) | KCNK9NPC1RAB9ANR1H4HDAC3 | |
| SCHEMBL30994891 | 0.83 | KCNK9 (0.72) | KCNK9NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582969-A | Application of acylthiourea compound in preparation of anti-enterovirus drugs | 武汉大学 | 2021-11-02 | — | — | CN | claimed |