Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.72 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.66 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.66 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250752 | 0.93 | KCNK9 (0.81) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL7303163 | 0.90 | HDAC3 (0.86) | HDAC3HDAC11HDAC8HDAC6NPC1 | |
| SCHEMBL30994891 | 0.90 | KCNK9 (0.72) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL19501539 | 0.90 | NR1H4 (0.73) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL12044572 | 0.90 | PTPN1 (0.70) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL28655554 | 0.89 | KCNK9 (0.67) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL3873116 | 0.87 | NR1H4 (0.81) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL7297239 | 0.87 | NR1H4 (0.81) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL2908907 | 0.87 | HDAC6 (0.74) | KCNK9HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL2345780 | 0.87 | EPHX1 (0.68) | KCNK9HDAC3HDAC11HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | claimed |
| CN-118048636-B | Electrocatalytic synthesis method for N-aryl amide | 平顶山学院 | 2024-09-13 | — | — | CN | disclosed |
| CN-118048636-A | Electrocatalytic synthesis method for N-aryl amide | 平顶山学院 | 2024-05-17 | — | — | CN | disclosed |
| CN-114276270-A | Synthesis method of compound with amido bond | 湖北文理学院 | 2022-04-05 | — | — | CN | disclosed |
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
| US-7799915-B2 | Anilino-pyrimidine analogs | WYETH LLC (US) | 2010-09-21 | — | — | US | disclosed |
| CN-100335468-C | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2007-09-05 | — | — | CN | disclosed |
| CN-1712398-A | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2005-12-28 | — | — | CN | disclosed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | KCNK9 2816/4885HDAC3 3413/4885HDAC11 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.