Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3400229 | 0.98 | SIRT1 (0.59) | EPHX2NR1H4SIRT1MEN1KMT2A | |
| SCHEMBL11665796 | 0.89 | MEN1 (0.71) | SIRT1MEN1KMT2ALMNAPOLB | |
| SCHEMBL3404122 | 0.88 | NR1H4 (0.60) | EPHX2NR1H4SIRT1MEN1KMT2A | |
| SCHEMBL7300203 | 0.87 | MEN1 (0.76) | EPHX2NR1H4MEN1KMT2ALMNA | |
| SCHEMBL7301203 | 0.87 | MEN1 (0.76) | EPHX2NR1H4MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL3400225 | 0.87 | SIRT1 (0.59) | EPHX2NR1H4SIRT1MEN1KMT2A | |
| SCHEMBL8218803 | 0.86 | NR1H4 (0.63) | EPHX2NR1H4SIRT1MEN1KMT2A | |
| SCHEMBL907336 | 0.85 | SIRT1 (0.64) | SIRT1MEN1KMT2ASIRT2LMNA | |
| SCHEMBL15149593 | 0.85 | MEN1 (0.54) | EPHX2NR1H4MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL3400231 | 0.84 | SIRT1 (0.62) | SIRT1MEN1KMT2ASIRT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724780-A | Acyl thiourea compound based on hydrophobic label, preparation method thereof and application of acyl thiourea compound in resisting influenza A virus | 武汉大学 | 2023-03-03 | — | — | CN | claimed |
| CN-115724780-B | Acylthiourea compound based on hydrophobic tag, preparation method thereof and application of acylthiourea compound in resisting influenza A virus | 武汉大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115724780-A | Acyl thiourea compound based on hydrophobic label, preparation method thereof and application of acyl thiourea compound in resisting influenza A virus | 武汉大学 | 2023-03-03 | — | — | CN | disclosed |
| US-8501991-B2 | P53 activating compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2013-08-06 | — | — | US | disclosed |
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-01-27 | — | — | US | disclosed |
| EP-2099445-B1 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIV DUNDEE (GB) | 2010-11-17 | — | — | EP | disclosed |
| EP-2099445-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | University Court of The University of Dundee (GB) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008029096-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021529-A1 | P53 ACTIVATING COMPOUNDS | TP53, TP53BP1, SIRT1 | EPHX2 4403/4885NR1H4 2245/4885SIRT1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.