Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287178 | 0.85 | — | — | |
| SCHEMBL28393659 | 0.85 | — | — | |
| SCHEMBL31384988 | 0.85 | — | — | |
| SCHEMBL31370338 | 0.71 | KDM4E (0.54) | MAPTKDM4ECYP2D6CYP2C19FFAR1 | |
| SCHEMBL7775272 | 0.71 | KDM4E (0.54) | MAPTKDM4ECYP2D6CYP2C19FFAR1 | |
| SCHEMBL7775270 | 0.71 | KDM4E (0.54) | MAPTKDM4ECYP2D6CYP2C19FFAR1 | |
| SCHEMBL1321720 | 0.69 | ALOX15 (1.00) | CYP2D6LMNABLMMEN1KMT2A | |
| SCHEMBL179767 | 0.69 | ALOX15 (1.00) | CYP2D6LMNABLMMEN1KMT2A | |
| SCHEMBL6745739 | 0.69 | ALOX15 (1.00) | CYP2D6LMNABLMMEN1KMT2A | |
| SCHEMBL179769 | 0.69 | ALOX15 (1.00) | CYP2D6LMNABLMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784961-A | Heteroaryl (heterocyclyl) carbinol compounds useful for treating hyperglycemia | 阿托基公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113784953-A | Heterocyclyl (phenyl) carbinol compounds useful for treating hyperglycemia | 阿托基公司 | 2021-12-10 | — | — | CN | disclosed |