SCHEMBL28655643

SCHEMBL28655643

O=c1c2ccccc2sc2c(O)cc(O)cc12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
MAPT P10636 5/20 0.72
POLB P06746 4/20 0.72
L3MBTL1 Q9Y468 2/20 0.72
HCRTR1 O43613 2/20 0.72
LMNA P02545 2/20 0.72
MAOA P21397 2/20 0.62
MAOB P27338 1/20 0.62
ESR2 Q92731 2/20 0.55
ESR1 P03372 1/20 0.55
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 3/20 0.43
HPGD P15428 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3881366 0.86 MAPT (0.53) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL28664644 0.85 ALDH1A1 (0.70) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL11994220 0.84 ALDH1A1 (0.64) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL1041154 0.84 MAPT (1.00) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL10001872 0.83 MAPT (0.62) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL44047 0.81 KDM4E (0.64) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL29518570 0.81 KDM4E (0.64) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL30162032 0.81 ALDH1A1 (0.55) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL8411752 0.81 ALDH1A1 (0.55) ALDH1A1MAPTPOLBL3MBTL1HCRTR1
SCHEMBL113420 0.80 ALDH1A1 (0.68) ALDH1A1MAPTPOLBL3MBTL1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113698382-B Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2022-06-14 CN claimed
CN-113698382-A Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2021-11-26 CN claimed
CN-118652361-A Application of novel disubstituted oxygen/thioxanthone high-efficiency visible light initiator in initiating vinyl photopolymerization system 湖北三峡实验室 2024-09-17 CN disclosed
CN-118598848-A Preparation method of novel disubstituted oxygen/thioxanthone high-efficiency visible light initiator and application of novel disubstituted oxygen/thioxanthone high-efficiency visible light initiator in acrylic ester photopolymerization system 湖北三峡实验室 2024-09-06 CN disclosed
CN-118598846-A Novel disubstituted oxygen/thioxanthone high-efficiency visible light initiator, preparation method and application thereof in thiol-olefin photopolymerization system 湖北三峡实验室 2024-09-06 CN disclosed
CN-118598847-A Application of novel disubstituted oxygen/thioxanthone high-efficiency visible light initiator in vinyl ether photopolymerization system 湖北三峡实验室 2024-09-06 CN disclosed
CN-113698382-B Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2022-06-14 CN disclosed
CN-113698382-B Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2022-06-14 CN disclosed
CN-113698382-A Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2021-11-26 CN disclosed
CN-113698382-A Novel thioxanthone visible light initiator and preparation method and application thereof 武汉大学 2021-11-26 CN disclosed