SCHEMBL8411752

SCHEMBL8411752

O=c1c2ccccc2sc2c(O)cccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPT P10636 4/20 0.55
POLB P06746 3/20 0.55
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HCRTR1 O43613 1/20 0.55
MAOA P21397 2/20 0.50
MAOB P27338 1/20 0.50
KDM4E B2RXH2 2/20 0.46
ALOX15 P16050 1/20 0.46
CYP19A1 P11511 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SAE1 Q9UBE0 1/20 0.45
UBA2 Q9UBT2 1/20 0.45
ESR2 Q92731 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30162032 1.00 ALDH1A1 (0.55) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL1587991 0.84 ALOX5 (0.57) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL30017926 0.82 ALDH1A1 (0.53) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL21624254 0.82 ALDH1A1 (0.53) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL18049827 0.81 ALOX5 (0.46) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL28655643 0.81 ALDH1A1 (0.72) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL5218956 0.80 MAOA (0.57) ALDH1A1MAPTPOLBLMNAL3MBTL1
Acetic Acid SCHEMBL28757869 0.79 PARP14 (0.56) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL11994220 0.78 ALDH1A1 (0.64) ALDH1A1MAPTPOLBLMNAL3MBTL1
SCHEMBL9851949 0.78 ALDH1A1 (0.47) ALDH1A1MAPTPOLBLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1723206-B High specificity anticancer pharmacological drug system, drug synthesis and drug formulation development method WALKER CANCER RES INST INC 2010-05-26 CN claimed
CN-1723206-A High specificity anticancer pharmacological drug system, drug synthesis and drug formulation development method WALKER CANCER RES INST INC (US) 2006-01-18 CN claimed
CN-119842345-A Composition capable of reducing internal stress of pressure-sensitive adhesive, preparation method and application of pressure-sensitive adhesive 广州鹿山新材料股份有限公司 2025-04-18 CN disclosed
US-20230159706-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS UNIVERSITE DE HAUTE ALSACE (FR) 2023-05-25 US disclosed
US-20230159706-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS UNIVERSITE DE HAUTE ALSACE (FR) 2023-05-25 US disclosed
US-20230159706-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS UNIVERSITE DE HAUTE ALSACE (FR) 2023-05-25 US disclosed
US-11629233-B2 Free-radical photoinitiators and uses of same in silicone compositions ELKEM SILICONES FRANCE SAS (FR) 2023-04-18 US disclosed
US-20210332191-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS ELKEM SILICONES FRANCE SAS (FR) 2021-10-28 US disclosed
US-20210332191-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS ELKEM SILICONES FRANCE SAS (FR) 2021-10-28 US disclosed
CN-111295379-A Free radical photoinitiators and their use in silicone compositions 埃肯有机硅法国简易股份公司 2020-06-16 CN disclosed
EP-3642192-A1 FREE-RADICAL PHOTOINITIATORS AND USES OF SAME IN SILICONE COMPOSITIONS Elkem Silicones France S.A.S. (FR) 2020-04-29 EP disclosed
CN-1723206-A High specificity anticancer pharmacological drug system, drug synthesis and drug formulation development method WALKER CANCER RES INST INC (US) 2006-01-18 CN disclosed
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP disclosed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO disclosed
CN-1020454-C THIOXANTHONE DERIVATIVES WARD BLENKINSOP & CO LTD (GB) 1993-05-05 CN disclosed
EP-0441221-A1 Method for preventing the appearance of efflorescence of mineral substrates BASF Aktiengesellschaft (DE) 1991-08-14 EP disclosed
EP-0224967-B1 THIOXANTHONE DERIVATIVES WARD BLENKINSOP AND COMPANY LIMITED (GB) 1989-07-19 EP disclosed
US-4791213-A PHOTOINITIATORS WARD BLENKINSOP & COMPANY LIMITED (GB) 1988-12-13 US disclosed
CN-86107935-A THIOXANTHONE DERIVATIVES 1987-07-08 CN disclosed
EP-0224967-A1 Thioxanthone derivatives WARD BLENKINSOP AND COMPANY LIMITED (GB) 1987-06-10 EP disclosed