SCHEMBL28655810

SCHEMBL28655810

CC(C)(CN1C(=O)c2ccccc2C1=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
CHRM2 P08172 1/20 0.48
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28650967 0.81 CA12 (0.50) CA12CA9MEN1KMT2ARAB9A
SCHEMBL1889560 0.81 CA12 (0.46) CA12CA9RAB9ANPC1CHRM2
SCHEMBL6389352 0.80 CA12 (0.49) CA12CA9MEN1KMT2ARAB9A
SCHEMBL13484325 0.79 ALDH1A1 (0.52) CA12CA9MEN1KMT2ACHRM2
SCHEMBL3170290 0.79 ALDH1A1 (0.52) CA12CA9MEN1KMT2ACHRM2
SCHEMBL5962347 0.79 CHRM2 (0.54) CA12CA9MEN1KMT2ACHRM2
SCHEMBL9625482 0.79 CHRM2 (0.63) MEN1KMT2ACHRM2ALDH1A1
SCHEMBL291933 0.79 CA12 (0.55) CA12CA9MEN1KMT2ARAB9A
SCHEMBL31385569 0.79 CA12 (0.55) CA12CA9MEN1KMT2ARAB9A
SCHEMBL9349967 0.78 TDP1 (0.55) MEN1KMT2ACHRM2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113668004-A Method for electrochemically synthesizing non-natural amino acid derivatives 浙江工业大学 2021-11-19 CN disclosed