Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28655837

O=C(O)C(F)(F)F.Oc1ccncn1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.42
UBE2N P61088 1/20 0.40
P2RX7 Q99572 1/20 0.38
CYP2D6 P10635 1/20 0.38
DPP4 P27487 1/20 0.38
KCNH2 Q12809 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
PLOD2 O00469 1/20 0.37
PLOD3 O60568 1/20 0.37
PLOD1 Q02809 1/20 0.37
KDM1A O60341 1/20 0.37
HSP90AA1 P07900 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
PAX8 Q06710 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL10512128 0.81 HSP90AA1 (0.44) P2RX7CYP2D6PLOD2PLOD3PLOD1
SCHEMBL29725232 0.81
SCHEMBL102661 0.81
Trifluoroacetic Acid SCHEMBL5263220 0.79 HSP90AA1 (0.63) L3MBTL1UBE2NP2RX7CYP2D6DPP4
Trifluoroacetic Acid SCHEMBL29630876 0.79 HSP90AA1 (0.63) L3MBTL1UBE2NP2RX7CYP2D6DPP4
Trifluoroacetic Acid SCHEMBL27742143 0.79 P2RX7 (0.49) L3MBTL1P2RX7CYP2D6DPP4KCNH2
Trifluoroacetic Acid SCHEMBL30581171 0.79 P2RX7 (0.49) L3MBTL1P2RX7CYP2D6DPP4KCNH2
Hydrochloric Acid SCHEMBL6215572 0.79
Bromide SCHEMBL28363832 0.79
Hydrochloric Acid SCHEMBL30706493 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112996794-A Fused heterocyclic compounds as RET kinase inhibitors 阿雷生物药品公司 2021-06-18 CN disclosed