Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5263220 | 1.00 | HSP90AA1 (0.63) | HSP90AA1P2RX7CDK5CDK5R1CYP2D6 | |
| Acetic Acid SCHEMBL6625265 | 0.82 | HSP90AA1 (0.71) | HSP90AA1P2RX7L3MBTL1GABRPGABRD | |
| Acetic Acid SCHEMBL6624458 | 0.82 | HSP90AA1 (0.71) | HSP90AA1P2RX7L3MBTL1GABRPGABRD | |
| Bicarbonate SCHEMBL28214447 | 0.81 | HSP90AA1 (0.68) | HSP90AA1P2RX7L3MBTL1GABRPGABRD | |
| Benzene SCHEMBL28103569 | 0.80 | HSP90AA1 (0.90) | HSP90AA1P2RX7CYP2D6KMT2AALDH1A1 | |
| SCHEMBL29761092 | 0.79 | — | — | |
| SCHEMBL94013 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL28655837 | 0.79 | L3MBTL1 (0.42) | HSP90AA1P2RX7CYP2D6DPP4KCNH2 | |
| Maleic Acid SCHEMBL27555039 | 0.79 | HSP90AA1 (0.65) | HSP90AA1P2RX7L3MBTL1GABRPGABRD | |
| Maleic Acid SCHEMBL27555040 | 0.79 | HSP90AA1 (0.65) | HSP90AA1P2RX7L3MBTL1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253384-A1 | METHOD FOR PREPARING BTK DEGRADING AGENT | Haisco Pharmaceuticals Pte. Ltd. (SG) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022111447-A1 | METHOD FOR PREPARING BTK DEGRADING AGENT | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |