SCHEMBL28656102

SCHEMBL28656102

C/C=C/C=C/C(=O)O[Si](CC)(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
CNR2 P34972 4/20 0.31
CNR1 P21554 2/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370169 0.83 HCAR2 (0.39)
SCHEMBL4409083 0.77 LMNA (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL4646881 0.76
SCHEMBL476044 0.73 HCAR2 (0.57) LMNAHTT
SCHEMBL28674916 0.73 LMNA (0.33) LMNAMAPK1HTT
SCHEMBL475934 0.73 HCAR2 (0.57) LMNAHTT
SCHEMBL475937 0.73 HCAR2 (0.57) LMNAHTT
SCHEMBL345936 0.72 HCAR2 (0.56) LMNAMAPK1HTT
SCHEMBL345935 0.72 HCAR2 (0.56) LMNAMAPK1HTT
SCHEMBL11792235 0.72 HCAR2 (0.56) LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113736001-B Application of Lewis base, sorbate polymer and derivative thereof 吉林大学 2022-07-01 CN disclosed
CN-113736001-A Application of Lewis base, sorbate polymer and derivative thereof 吉林大学 2021-12-03 CN disclosed