Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435539 | 0.88 | CNR1 (0.67) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6431976 | 0.79 | CNR1 (0.63) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6432059 | 0.78 | CNR1 (0.61) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL20077094 | 0.76 | LMNA (0.53) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL28654016 | 0.75 | CNR1 (0.46) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL23903534 | 0.74 | CNR1 (0.65) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6188978 | 0.74 | LMNA (0.55) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL25443355 | 0.72 | CNR1 (0.58) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL6360344 | 0.72 | NPC1 (0.75) | HDAC3HDAC1HDAC2ALDH1A1NPC1 | |
| SCHEMBL23903290 | 0.72 | CNR1 (0.61) | CNR1CNR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |