SCHEMBL2865619

SCHEMBL2865619

OOc1cccc2c1-c1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA12 O43570 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA4 P22748 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ORAI1 Q96D31 1/20 0.40
ORAI2 Q96SN7 1/20 0.40
ORAI3 Q9BRQ5 1/20 0.40
PDK2 Q15119 1/20 0.40
TOP1 P11387 1/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 1/20 0.39
EGFR P00533 1/20 0.39
PIM1 P11309 1/20 0.39
ALDH1A1 P00352 6/20 0.39
MAPT P10636 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16174455 0.83 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL5576493 0.83 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL10883271 0.83 MAPT (0.52) MEN1KMT2ATP53EGFRPIM1
Ethane SCHEMBL29030193 0.81 CA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL491473 0.80 CA1 (0.39) CA1CA2CA7CA9CA12
SCHEMBL1675994 0.77 TSHR (0.46) KMT2ATSHRALDH1A1MAPK1HPGD
SCHEMBL27512237 0.77 KDM4E (0.52) MEN1KMT2ATP53TSHRPIM1
SCHEMBL2146501 0.76 TOP1 (0.39) CA1CA2CA7CA9CA12
SCHEMBL28033655 0.76 CA1 (0.36) CA1CA2CA7CA9CA12
SCHEMBL16174477 0.76 PDK2 (0.51) MEN1KMT2APDK2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754844-B2 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-07-13 US claimed
EP-1561768-B1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE TOYO BOSEKI (JP) 2009-09-30 EP claimed
US-20060166048-A1 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-07-27 US claimed
EP-1561768-A1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE Toyo Boseki Kabushiki Kaisha (JP) 2005-08-10 EP claimed
US-7754844-B2 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-07-13 US disclosed
EP-1561768-B1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE TOYO BOSEKI (JP) 2009-09-30 EP disclosed
US-20060166048-A1 Polyarylene ether compound containing sulfonic acid group, composition containing same, and method for manufacturing those TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-07-27 US disclosed
EP-1561768-A1 POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE Toyo Boseki Kabushiki Kaisha (JP) 2005-08-10 EP disclosed
JP-2004263167-A AROMATIC POLYETHER-BASED COMPOUND CONTAINING SULFONIC GROUP, ITS COMPOSITE, AND PREPARING PROCESSES FOR THEM TOYOBO CO LTD 2004-09-24 JP disclosed