SCHEMBL10883271

SCHEMBL10883271

O=C1c2ccccc2-c2cccc(OO)c21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.52
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
ALDH1A1 P00352 7/20 0.52
TDP1 Q9NUW8 4/20 0.52
KDM4E B2RXH2 3/20 0.52
USP2 O75604 1/20 0.52
DUSP3 P51452 1/20 0.52
LMNA P02545 4/20 0.52
NPC1 O15118 4/20 0.51
EGFR P00533 3/20 0.50
PIM1 P11309 1/20 0.50
MAOA P21397 2/20 0.47
RAB9A P51151 7/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
MAPK1 P28482 4/20 0.46
POLB P06746 3/20 0.46
BLM P54132 2/20 0.46
THRB P10828 2/20 0.46
PPARG P37231 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183075 0.92 MAPT (0.54) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL28037979 0.90 MAPT (0.53) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL27961928 0.90 MAPT (0.53) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL9264626 0.84 MAPT (0.74) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL11565971 0.83 MAPT (0.50) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL2865619 0.83 CA1 (0.42) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL28569052 0.80 MAPT (0.68) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL7479718 0.79 ALDH1A1 (0.56) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL29126288 0.78 MAPT (0.66) MAPTMEN1KMT2AALDH1A1TDP1
SCHEMBL28573446 0.78 MAPT (0.66) MAPTMEN1KMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015181116-A1 PROCESS AND INTERMEDIADES FOR THE PREPARATION OF 7-ALKYLATED STEROIDS CRYSTAL PHARMA, S.A.U. (ES) 2015-12-03 WO disclosed
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed