Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 13/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951 | 0.84 | RAPGEF4 (0.59) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL1551822 | 0.84 | RAPGEF4 (0.59) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL5180888 | 0.81 | RAPGEF4 (0.56) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL28482658 | 0.81 | RAPGEF4 (0.56) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL10412763 | 0.81 | RAPGEF4 (0.56) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL6255294 | 0.78 | RAPGEF4 (0.53) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL18044240 | 0.74 | RAPGEF4 (0.38) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL30380206 | 0.74 | RAPGEF4 (0.38) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL4701345 | 0.73 | RAPGEF4 (0.48) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL10659964 | 0.73 | RAPGEF4 (0.48) | RAPGEF4CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294776-B | Method for preparing aryl phosphine oxide derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |