Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 12/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951 | 0.93 | RAPGEF4 (0.59) | RAPGEF4TSHRACHECA1CA2 | |
| SCHEMBL1551822 | 0.93 | RAPGEF4 (0.59) | RAPGEF4TSHRACHECA1CA2 | |
| SCHEMBL10412763 | 0.89 | RAPGEF4 (0.56) | RAPGEF4TSHRACHECA1CA2 | |
| SCHEMBL28482658 | 0.89 | RAPGEF4 (0.56) | RAPGEF4TSHRACHECA1CA2 | |
| SCHEMBL5180888 | 0.89 | RAPGEF4 (0.56) | RAPGEF4TSHRACHECA1CA2 | |
| Hexamethylbenzene SCHEMBL9614359 | 0.82 | RAPGEF4 (0.43) | RAPGEF4ACHECA1CA2MMP1 | |
| SCHEMBL9431076 | 0.81 | ALDH1A1 (0.53) | RAPGEF4TSHRCYP3A4MAPK1ACHE | |
| SCHEMBL10659964 | 0.80 | RAPGEF4 (0.48) | RAPGEF4ACHECA1CA2MMP1 | |
| SCHEMBL4701345 | 0.80 | RAPGEF4 (0.48) | RAPGEF4ACHECA1CA2MMP1 | |
| SCHEMBL11220843 | 0.78 | RAPGEF4 (0.39) | RAPGEF4TSHRACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574495-A1 | Adamantane derivatives | Daicel Chemical Industries, Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
| US-5298565-A | Polymerization of nitrogen containing monomer onto hydrocarbon backbone, aromatic solvent for hydrogen atom chain transfer | THE LUBRIZOL CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |