Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | CDC25A | P30304 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19478231 | 0.91 | MAPT (0.56) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL11691658 | 0.81 | MAPT (0.63) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17492955 | 0.80 | PIM1 (0.48) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL1149730 | 0.79 | MAPT (0.66) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Hydrochloric Acid SCHEMBL1488003 | 0.79 | PIM1 (0.47) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8341400 | 0.78 | MAPT (0.69) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL18601895 | 0.78 | MAPT (0.65) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL19461410 | 0.77 | MAPT (0.61) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL23198991 | 0.77 | EPHX2 (0.65) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3191867 | 0.77 | EPHX2 (0.57) | MAPTMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559198-A | Medicine special for treating lumbar disc herniation | 杨守信 | 2021-10-29 | — | — | CN | disclosed |