Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | CDC25A | P30304 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656542 | 0.91 | PDE4A (0.55) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11691658 | 0.86 | MAPT (0.63) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8341400 | 0.80 | MAPT (0.69) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19461410 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17492955 | 0.78 | PIM1 (0.48) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18601894 | 0.78 | RAB9A (0.62) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6361693 | 0.78 | EPHX2 (0.67) | MAPTMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL1488003 | 0.77 | PIM1 (0.47) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1149730 | 0.77 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29906115 | 0.76 | SMN1; SMN2 (0.70) | MAPTMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445382-B1 | HARUNGANA MADAGASCARIENSIS LEAF EXTRACT FOR USE IN THE TREATMENT AND/OR PREVENTION OF ACNE | SOCIÉTÉ D'EXPLOITATION DE PRODUITS POUR LES IND CHIMIQUES SEPPIC (FR) | 2020-09-09 | — | — | EP | disclosed |
| CN-109069563-A | For treating and/or preventing Madagascar's Ha Lunjiana leaf extract of acne | 化工产品开发公司SEPPIC | 2018-12-21 | — | — | CN | disclosed |
| WO-2017182182-A1 | HARUNGANA MADAGASCARIENSIS LEAF EXTRACT FOR USE IN THE TREATMENT AND/OR PREVENTION OF ACNE | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2017-10-26 | — | — | WO | disclosed |