Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.78 |
| ▸ | PPARG | P37231 | 16/20 | 0.77 |
| ▸ | PPARA | Q07869 | 8/20 | 0.65 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663294 | 0.87 | PPARG (1.00) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL23015873 | 0.83 | PPARG (1.00) | EPHX2PPARGPPARA | |
| SCHEMBL1511311 | 0.80 | PPARG (0.49) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL28647893 | 0.80 | PPARG (1.00) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL2905172 | 0.79 | KMT2A (0.77) | EPHX2 | |
| SCHEMBL22987232 | 0.79 | EPHX2 (0.67) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL28658560 | 0.79 | PPARG (1.00) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL28662967 | 0.78 | PPARG (0.81) | EPHX2PPARGPPARAPPARD | |
| SCHEMBL28665658 | 0.77 | KMT2A (0.65) | EPHX2 | |
| SCHEMBL7386121 | 0.74 | CYP1A2 (0.55) | EPHX2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |