Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905172 | 0.84 | KMT2A (0.77) | KMT2AEPHX2HDAC6HDAC1HDAC2 | |
| SCHEMBL28643598 | 0.82 | ALDH1A1 (0.72) | EPHX2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL5642848 | 0.82 | KMT2A (0.68) | KMT2AEPHX2HDAC1ALDH1A1TTR | |
| SCHEMBL22987232 | 0.82 | EPHX2 (0.67) | KMT2AEPHX2HDAC6HDAC1HDAC2 | |
| SCHEMBL28648926 | 0.80 | HDAC6 (0.70) | EPHX2HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL28648931 | 0.79 | KMT2A (0.65) | KMT2AEPHX2HDAC6HDAC1HDAC2 | |
| SCHEMBL28656782 | 0.77 | EPHX2 (0.78) | EPHX2 | |
| SCHEMBL29258097 | 0.75 | NAMPT (0.76) | KMT2A | |
| SCHEMBL28710986 | 0.74 | KMT2A (0.62) | KMT2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL2456852 | 0.72 | KMT2A (0.58) | KMT2AEPHX2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |