Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.79 |
| ▸ | PPARA | Q07869 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656782 | 0.87 | EPHX2 (0.78) | PPARGEPHX2PPARAPPARD | |
| SCHEMBL23015873 | 0.84 | PPARG (1.00) | PPARGEPHX2PPARA | |
| SCHEMBL28647893 | 0.81 | PPARG (1.00) | PPARGEPHX2PPARAPPARD | |
| SCHEMBL4521046 | 0.80 | ALDH1A1 (1.00) | PPARGEPHX2ALDH1A1HPGDKDM4E | |
| SCHEMBL9419792 | 0.80 | PPARG (0.64) | PPARGEPHX2PPARAALDH1A1HPGD | |
| SCHEMBL28658560 | 0.80 | PPARG (1.00) | PPARGEPHX2PPARAHPGDPPARD | |
| SCHEMBL28662967 | 0.79 | PPARG (0.81) | PPARGEPHX2PPARALMNAPPARD | |
| SCHEMBL28643598 | 0.78 | ALDH1A1 (0.72) | PPARGEPHX2ALDH1A1HPGDKDM4E | |
| SCHEMBL4503669 | 0.76 | HPGD (0.79) | PPARGEPHX2ALDH1A1HPGDKDM4E | |
| SCHEMBL7384644 | 0.75 | PPARG (0.57) | PPARGEPHX2PPARAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |