Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 16/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644435 | 0.86 | LOX (0.71) | LOX | |
| SCHEMBL28652319 | 0.85 | CA2 (0.50) | LOXLOXL2CA2MAOA | |
| SCHEMBL19259607 | 0.82 | LOX (0.49) | LOXLOXL2CA2MAOA | |
| SCHEMBL28657398 | 0.79 | LOX (0.50) | LOXLOXL2CA2MAOA | |
| SCHEMBL19274437 | 0.79 | LOX (0.44) | LOXLOXL2CA2 | |
| SCHEMBL28663727 | 0.74 | LOX (0.47) | LOXLOXL2MAOA | |
| SCHEMBL28643852 | 0.72 | LOX (0.59) | LOXLOXL2 | |
| SCHEMBL19259610 | 0.72 | LOX (0.38) | LOXLOXL2CA2MAOA | |
| SCHEMBL28657374 | 0.72 | LOX (0.68) | LOXLOXL2CA2 | |
| SCHEMBL28663650 | 0.72 | LOX (0.57) | LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |