SCHEMBL2865765

SCHEMBL2865765

Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(OC2CCOC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.59
SLC5A1 P13866 14/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13160938 1.00 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL17275499 0.93 SLC5A2 (0.66) SLC5A2SLC5A1
SCHEMBL17275498 0.93 SLC5A2 (0.66) SLC5A2SLC5A1
SCHEMBL17267534 0.93 SLC5A2 (0.66) SLC5A2SLC5A1
SCHEMBL17267535 0.93 SLC5A2 (0.66) SLC5A2SLC5A1
SCHEMBL13947258 0.91 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL1457455 0.91 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL22721955 0.90 SLC5A2 (0.58) SLC5A2SLC5A1
SCHEMBL22721958 0.90 SLC5A2 (0.58) SLC5A2SLC5A1
SCHEMBL22721937 0.88 SLC5A2 (0.57) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442795-B2 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2019-10-15 US disclosed
EP-1881990-B1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN BOEHRINGER INGELHEIM INT (DE) 2016-02-17 EP disclosed
US-20150322053-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN BOEHRINGER INGELHEIM INT (DE) 2015-11-12 US disclosed
US-9127034-B2 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivates and intermediates therein BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-08 US disclosed
US-20100240879-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-09-23 US disclosed
US-7772191-B2 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-08-10 US disclosed
EP-1881990-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN Boehringer Ingelheim International GmbH (DE) 2008-01-30 EP disclosed
WO-2006120208-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-11-16 WO disclosed
US-20060258749-A1 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258749-A1 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein UGGT1, B3GAT3, B4GALT1 SLC5A2 120/4885SLC5A1 111/4885
US-20100240879-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN UGGT1, B3GAT3, B4GALT1 SLC5A2 123/4885SLC5A1 85/4885
US-10442795-B2 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein UGGT1, B3GAT3, B4GALT1 SLC5A2 120/4885SLC5A1 111/4885
US-20150322053-A1 PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN UGGT1, B3GAT3, B4GALT1 SLC5A2 120/4885SLC5A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.