Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315982 | 0.88 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL27448763 | 0.75 | KCNN4 (0.44) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| SCHEMBL27467077 | 0.75 | KCNN4 (0.46) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| SCHEMBL18113458 | 0.71 | KCNN4 (0.46) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| SCHEMBL31560841 | 0.71 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| SCHEMBL11826461 | 0.70 | KCNN4 (0.45) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| SCHEMBL17420795 | 0.70 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL31414989 | 0.70 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL1702810 | 0.70 | KCNN4 (0.45) | KCNN4HDAC3HDAC1HDAC2KCNE1 | |
| Bromoethane SCHEMBL3813957 | 0.69 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382754-A | Compounds, compositions, methods and uses for treating cancer and immune disorders | IL-2RX公司 | 2021-09-10 | — | — | CN | disclosed |