Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentane SCHEMBL28658226 | 0.88 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL17420795 | 0.79 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL31414989 | 0.79 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL31560841 | 0.76 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL3818506 | 0.75 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL29009831 | 0.74 | CYP1A2 (0.48) | KCNN4CES1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4660655 | 0.74 | CYP1A2 (0.48) | KCNN4CES1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7178206 | 0.73 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL30501782 | 0.73 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1CES1CES2 | |
| SCHEMBL1239901 | 0.73 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553107-B1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | PROCYON PHARM INC (US) | 1999-09-29 | — | — | EP | claimed |