Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655618 | 0.81 | KCNN4 (0.49) | KCNN4PDE2ARORC | |
| SCHEMBL28662168 | 0.76 | KCNN4 (0.45) | KCNN4EPHX1NR3C2PDE2AHDAC3 | |
| SCHEMBL27686522 | 0.76 | KCNN4 (0.44) | KCNN4ARTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28649324 | 0.75 | KDM1A (0.48) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28650706 | 0.75 | VNN1 (0.34) | KCNN4ARNR3C2KMOHDAC3 | |
| SCHEMBL22470257 | 0.75 | KCNN4 (0.46) | KCNN4ARTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL22470408 | 0.75 | KCNN4 (0.41) | KCNN4EPHX1ARNR3C2TAS1R3 | |
| Hydrochloric Acid SCHEMBL31627334 | 0.74 | LMNA (0.49) | KCNN4EPHX1ARTAS1R3TAS1R1 | |
| SCHEMBL31216497 | 0.74 | KCNN4 (0.43) | KCNN4EPHX1ARNR3C2TAS1R3 | |
| SCHEMBL28876275 | 0.73 | APP (0.58) | KCNN4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | claimed |
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |