Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.62 |
| ▸ | VHL | P40337 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263314 | 1.00 | AR (0.62) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL22263276 | 1.00 | AR (0.62) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL26464308 | 0.91 | AR (0.57) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL30219489 | 0.91 | AR (0.57) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL26464414 | 0.90 | AR (0.60) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL30291247 | 0.89 | AR (0.59) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL30219491 | 0.89 | AR (0.59) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL30617816 | 0.89 | AR (0.59) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL30291248 | 0.89 | AR (0.59) | ARVHLRAB9ANPC1LMNA | |
| SCHEMBL25942618 | 0.89 | AR (0.59) | ARVHLRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677668-A | Bifunctional compounds and methods for androgen receptor targeted ubiquitination | 蒙特利诺治疗公司 | 2021-11-19 | — | — | CN | disclosed |