Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.59 |
| ▸ | VHL | P40337 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25942618 | 1.00 | AR (0.59) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL30617816 | 1.00 | AR (0.59) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL30219491 | 1.00 | AR (0.59) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL30291247 | 1.00 | AR (0.59) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL30219486 | 0.93 | AR (0.61) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL26464151 | 0.93 | AR (0.61) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL26464411 | 0.89 | AR (0.57) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL22263276 | 0.89 | AR (0.62) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL22263314 | 0.89 | AR (0.62) | ARVHLRAF1BRAFNPC1 | |
| SCHEMBL28658355 | 0.89 | AR (0.62) | ARVHLRAF1BRAFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039603-A2 | BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR | MONTELINO THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |