Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 11/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658604 | 1.00 | TDP1 (0.47) | TDP1HPGDNAMPTSLC22A12MEN1 | |
| SCHEMBL28655184 | 0.83 | TDP1 (0.63) | TDP1HPGDMEN1KMT2ANLN | |
| SCHEMBL16219054 | 0.83 | NAMPT (0.57) | HPGDNAMPTSLC22A12ACEGAA | |
| SCHEMBL28676326 | 0.83 | NAMPT (0.44) | TDP1HPGDNAMPT | |
| SCHEMBL30445878 | 0.79 | HPGD (0.50) | HPGDNAMPTSLC22A12MEN1KMT2A | |
| SCHEMBL16219038 | 0.78 | NAMPT (0.57) | HPGDNAMPTSLC22A12ACEGAA | |
| SCHEMBL18205136 | 0.78 | NAMPT (0.47) | HPGDNAMPTSLC22A12ACEGAA | |
| SCHEMBL28673309 | 0.77 | PRMT5 (0.43) | NAMPT | |
| SCHEMBL28673307 | 0.77 | PRMT5 (0.43) | NAMPT | |
| SCHEMBL14970362 | 0.76 | NOTUM (0.63) | HPGDNAMPTSLC22A12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |