Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673309 | 1.00 | PRMT5 (0.43) | PRMT5WDR77NAMPTHDAC4KDM4E | |
| SCHEMBL28654413 | 0.84 | CARM1 (0.51) | PRMT5WDR77 | |
| SCHEMBL28654411 | 0.84 | CARM1 (0.51) | PRMT5WDR77 | |
| SCHEMBL28654076 | 0.83 | HDAC4 (0.42) | PRMT5WDR77NAMPTHDAC4KDM4E | |
| SCHEMBL18212477 | 0.79 | PRMT5 (0.45) | PRMT5WDR77NAMPTHDAC4 | |
| SCHEMBL28668552 | 0.79 | PRMT5 (0.45) | PRMT5WDR77NAMPTHDAC4 | |
| SCHEMBL18212476 | 0.79 | NAMPT (0.49) | PRMT5WDR77NAMPTHDAC4 | |
| Hydrochloric Acid SCHEMBL18205144 | 0.78 | PRMT5 (0.44) | PRMT5WDR77NAMPTHDAC4 | |
| Hydrochloric Acid SCHEMBL18205147 | 0.78 | PRMT5 (0.44) | PRMT5WDR77NAMPTHDAC4 | |
| SCHEMBL28658606 | 0.77 | TDP1 (0.47) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |