Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650972 | 0.85 | TDP1 (0.57) | TDP1HPGD | |
| SCHEMBL28658606 | 0.83 | TDP1 (0.47) | NAMPTTDP1HPGD | |
| SCHEMBL28658604 | 0.83 | TDP1 (0.47) | NAMPTTDP1HPGD | |
| SCHEMBL28676327 | 0.80 | NAMPT (0.44) | NAMPTHCRTR2 | |
| SCHEMBL18215073 | 0.80 | NAMPT (0.44) | NAMPTHCRTR2 | |
| SCHEMBL29758943 | 0.80 | NAMPT (0.44) | NAMPTHCRTR2 | |
| SCHEMBL25518873 | 0.80 | NAMPT (0.56) | NAMPT | |
| SCHEMBL28654076 | 0.80 | HDAC4 (0.42) | NAMPT | |
| SCHEMBL28668562 | 0.79 | DPP8 (0.48) | NAMPTTDP1HPGD | |
| SCHEMBL16219054 | 0.78 | NAMPT (0.57) | NAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |