Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | BCL6 | P41182 | 3/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658660 | 0.91 | BCHE (0.49) | BCHEACHEDYRK1AMAOABRD4 | |
| SCHEMBL28650581 | 0.91 | BCHE (0.49) | BCHEACHEDYRK1AMAOABRD4 | |
| SCHEMBL28654213 | 0.91 | BCHE (0.51) | BCHEACHEDYRK1AMAOABRD4 | |
| SCHEMBL28654952 | 0.88 | BCHE (0.46) | BCHEACHEDYRK1AMAOABCL6 | |
| SCHEMBL28654962 | 0.84 | BCHE (0.46) | BCHEACHEDYRK1AMAOALCK | |
| SCHEMBL28673143 | 0.80 | PDE1C (0.38) | BCHEACHEDYRK1ABRD4LCK | |
| SCHEMBL28660781 | 0.73 | MAOA (0.47) | BCHEACHEDYRK1AMAOAHASPIN | |
| SCHEMBL28650153 | 0.71 | BCHE (0.52) | BCHEACHEDYRK1AMAOAHASPIN | |
| SCHEMBL28929340 | 0.70 | ACHE (0.65) | BCHEACHEDYRK1AMAOAHASPIN | |
| SCHEMBL31484282 | 0.69 | KMT2A (0.50) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393438-B | Preparation method and application of 6-substituted-beta-carboline alkali compound and derivative | 石河子大学 | 2021-11-30 | — | — | CN | disclosed |