Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450184 | 1.00 | HDAC8 (0.51) | HDAC8ACHEBCHEOPRM1SIGMAR1 | |
| SCHEMBL28670402 | 0.88 | HDAC8 (0.54) | HDAC8ACHECCR3MEN1KMT2A | |
| SCHEMBL22291039 | 0.80 | HDAC8 (0.60) | HDAC8ACHEBCHESIGMAR1CCR3 | |
| SCHEMBL31728335 | 0.75 | S1PR4 (0.48) | ACHEBCHEOPRM1SIGMAR1CCR3 | |
| SCHEMBL29985314 | 0.75 | SIGMAR1 (0.45) | ACHESIGMAR1MEN1KMT2A | |
| SCHEMBL6745643 | 0.75 | HDAC8 (0.64) | HDAC8ACHEBCHEOPRM1SIGMAR1 | |
| SCHEMBL6745644 | 0.75 | HDAC8 (0.64) | HDAC8ACHEBCHEOPRM1SIGMAR1 | |
| SCHEMBL7374032 | 0.74 | ACHE (0.57) | HDAC8ACHEBCHESIGMAR1CCR3 | |
| SCHEMBL6983979 | 0.73 | HDAC8 (0.60) | HDAC8ACHEBCHESIGMAR1CCR3 | |
| SCHEMBL6983982 | 0.73 | HDAC8 (0.60) | HDAC8ACHEBCHESIGMAR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677350-A | ENPP1 inhibitors and methods of modulating immune responses | 里兰斯坦福初级大学理事会 | 2021-11-19 | — | — | CN | disclosed |