Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739253 | 0.76 | CALM1 (0.43) | IDO1LOXL2TAAR1MAOBTRPA1 | |
| SCHEMBL25263956 | 0.76 | CALM1 (0.43) | IDO1LOXL2TAAR1MAOBTRPA1 | |
| SCHEMBL19260349 | 0.70 | IDO1 (0.48) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| SCHEMBL28314301 | 0.69 | IDO1 (0.39) | IDO1LOXL2TAAR1AGXT | |
| Potassium Ion SCHEMBL19260323 | 0.68 | IDO1 (0.46) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| SCHEMBL1468357 | 0.67 | IDO1 (0.58) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| SCHEMBL7437052 | 0.67 | TAAR1 (0.68) | IDO1LOXL2TAAR1AGXTMAOB | |
| SCHEMBL16561361 | 0.67 | IDO1 (0.58) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| Lithium Ion SCHEMBL7741416 | 0.67 | IDO1 (0.50) | IDO1LOXL2TAAR1AGXTPLA2G1B | |
| SCHEMBL7719447 | 0.67 | IDO1 (0.50) | IDO1LOXL2TAAR1AGXTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071562-B | Fused 1, 4-oxazepine and related analogs as BET bromodomain inhibitors | 密执安大学评议会 | 2022-03-22 | — | — | CN | disclosed |
| CN-110294776-B | Method for preparing aryl phosphine oxide derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |