Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929650 | 0.70 | MEN1 (0.40) | KMT2AMEN1NR2F2ALDH1A1TSHR | |
| SCHEMBL28676899 | 0.70 | ALDH1A1 (0.42) | KMT2AMEN1NR2F2ALDH1A1TSHR | |
| SCHEMBL1003427 | 0.68 | PARN (0.48) | KMT2AMEN1NR2F2ALDH1A1KDM4E | |
| SCHEMBL8985073 | 0.67 | GSK3B (0.67) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2464129 | 0.65 | MEN1 (1.00) | KMT2AMEN1NR2F2TSHRKDM4E | |
| SCHEMBL5763739 | 0.63 | MEN1 (0.52) | KMT2AMEN1NR2F2ALDH1A1TSHR | |
| SCHEMBL7035174 | 0.63 | PDE10A (0.56) | KMT2AMEN1NR2F2TSHRKDM4E | |
| SCHEMBL19378208 | 0.63 | SMN1; SMN2 (0.40) | KMT2AMEN1NR2F2ALDH1A1TSHR | |
| SCHEMBL2965839 | 0.62 | ADORA3 (0.47) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL1945875 | 0.62 | KMT2A (0.69) | KMT2AMEN1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608462-B | 7-alkyl-9-alkoxy/thiopurine-8-ketone compound, and synthesis method and application thereof in medicines | 华南理工大学 | 2021-11-23 | — | — | CN | disclosed |