Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876413 | 0.83 | NPSR1 (0.32) | CACNA1H | |
| SCHEMBL2870191 | 0.80 | PTGES (0.31) | RHEB | |
| SCHEMBL2873807 | 0.78 | AAK1 (0.35) | TDP1 | |
| SCHEMBL2870041 | 0.77 | CACNA1B (0.46) | CACNA1H | |
| Methyl Alcohol SCHEMBL2876053 | 0.71 | CACNA1H (0.31) | CACNA1H | |
| SCHEMBL2872671 | 0.71 | — | — | |
| SCHEMBL2878991 | 0.70 | C5AR1 (0.41) | — | |
| SCHEMBL2870068 | 0.70 | ERN1 (0.30) | — | |
| SCHEMBL2876214 | 0.70 | LCK (0.31) | — | |
| SCHEMBL2875160 | 0.64 | MAPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |