Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870041 | 0.87 | CACNA1B (0.46) | CACNA1BCACNA1HCACNA1C | |
| SCHEMBL2865970 | 0.83 | CACNA1H (0.33) | CACNA1H | |
| SCHEMBL2866756 | 0.81 | SMN1; SMN2 (0.36) | NPSR1PTGESCCR2MTNR1AMTNR1B | |
| SCHEMBL2870191 | 0.75 | PTGES (0.31) | PTGES | |
| SCHEMBL2874900 | 0.72 | CACNA1H (0.41) | NPSR1CACNA1BCACNA1HCACNA1CMEN1 | |
| SCHEMBL2868954 | 0.72 | SMN1; SMN2 (0.36) | NPSR1PTGESCCR2MTNR1AMTNR1B | |
| SCHEMBL4531936 | 0.65 | EGLN1 (0.44) | CACNA1BCACNA1H | |
| SCHEMBL2874738 | 0.65 | PTGES (0.35) | PTGESMEN1KMT2A | |
| SCHEMBL16176683 | 0.65 | CACNA1B (0.54) | CACNA1BCACNA1HPTGESCCR2CACNA1C | |
| SCHEMBL2872637 | 0.64 | AAK1 (0.36) | NPSR1CACNA1BCACNA1HCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |