Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29053196 | 0.91 | MEN1 (0.59) | KMT2AMEN1PRSS1KDM4EALDH1A1 | |
| SCHEMBL4576561 | 0.83 | LMNA (0.54) | KMT2AMEN1MTNR1AMTNR1BKDM4E | |
| SCHEMBL4990119 | 0.82 | KMT2A (0.65) | KMT2AMEN1 | |
| SCHEMBL8155382 | 0.82 | SMN1; SMN2 (0.50) | PRSS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL79713 | 0.80 | KMT2A (0.61) | KMT2AMEN1 | |
| SCHEMBL19743595 | 0.80 | ACHE (0.52) | MTNR1AMTNR1BKDM4ENSD2ALDH1A1 | |
| SCHEMBL29053207 | 0.78 | MEN1 (0.59) | KMT2AMEN1PRSS1KDM4EALDH1A1 | |
| SCHEMBL7249861 | 0.78 | KMT2A (0.47) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL2721243 | 0.76 | KMT2A (0.66) | KMT2AMEN1PARP10 | |
| SCHEMBL28741221 | 0.75 | MEN1 (0.65) | KMT2AMEN1MTNR1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563073-B | For the treatment of para-5-HT1AReceptor-controlled serotonergic disease-modulating compounds | 诺罗利西斯公司 | 2021-12-07 | — | — | CN | disclosed |