Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666073 | 1.00 | ERN1 (0.49) | ERN1MEN1POLBPLCG1KMT2A | |
| SCHEMBL29903415 | 0.82 | BLM (0.59) | BLMNPSR1TSHRPKMCA12 | |
| SCHEMBL11138020 | 0.82 | BLM (0.59) | BLMNPSR1TSHRPKMCA12 | |
| SCHEMBL28661145 | 0.81 | ERN1 (0.49) | ERN1MEN1POLBPLCG1KMT2A | |
| SCHEMBL28669627 | 0.81 | ERN1 (0.49) | ERN1MEN1POLBPLCG1KMT2A | |
| SCHEMBL28562744 | 0.78 | PKM (0.46) | ERN1KMT2ABLMNPSR1TSHR | |
| SCHEMBL28562745 | 0.78 | PKM (0.46) | ERN1KMT2ABLMNPSR1TSHR | |
| SCHEMBL30973488 | 0.76 | ERN1 (0.50) | ERN1MEN1POLBPLCG1KMT2A | |
| SCHEMBL10499136 | 0.74 | TSHR (0.39) | BLMNPSR1TSHRKDM4EALDH1A1 | |
| SCHEMBL1541991 | 0.74 | ERN1 (0.64) | ERN1KMT2ATSHRPKMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666812-B | Synthesis method of 5-halogenated veratraldehyde | 四川大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113735847-B | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113735847-A | Synthetic preparation method of berberine hydrochloride | 四川大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113666812-A | Synthesis method of 5-halogenated veratraldehyde | 四川大学 | 2021-11-19 | — | — | CN | disclosed |