Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972130 | 0.76 | KMT2A (0.54) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL10341128 | 0.76 | KMT2A (0.54) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL30274517 | 0.75 | KMT2A (0.38) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| Iodide SCHEMBL10424612 | 0.74 | KMT2A (0.52) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL11515580 | 0.74 | KMT2A (0.37) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| Iodide SCHEMBL25336370 | 0.73 | TLR8 (0.42) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| Iodide SCHEMBL30510665 | 0.73 | TLR8 (0.42) | NOTUMSMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL28980139 | 0.71 | SIGMAR1 (0.44) | SMN1; SMN2MAPTALDH1A1KDM4EDRD2 | |
| SCHEMBL30242135 | 0.71 | SIGMAR1 (0.44) | SMN1; SMN2MAPTALDH1A1KDM4EDRD2 | |
| SCHEMBL30242141 | 0.70 | P2RX7 (0.39) | SMN1; SMN2MAPTKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467551-B | Preparation process of coumarin fluorescent probe molecule for selectively detecting GSH | 曲靖师范学院 | 2021-12-14 | — | — | CN | disclosed |