SCHEMBL28660601

SCHEMBL28660601

CC1(F)CCOC(c2ccc([N+](=O)[O-])cc2)C1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 3/20 0.38
EPHX1 P07099 1/20 0.38
RECQL P46063 2/20 0.37
HSD17B10 Q99714 2/20 0.37
POLB P06746 1/20 0.36
LMNA P02545 2/20 0.36
ACHE P22303 1/20 0.36
KDM1A O60341 1/20 0.35
SLC18A3 Q16572 1/20 0.34
CPB1 P15086 1/20 0.33
TRPA1 O75762 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28670836 0.84 KDM1A (0.46) KMT2AALDH1A1LMNAACHEKDM1A
SCHEMBL28687063 0.83 KMT2A (0.40) KMT2AMEN1ALDH1A1EPHX1RECQL
SCHEMBL28582566 0.83 MEN1 (0.40) KMT2AMEN1ALDH1A1EPHX1RECQL
SCHEMBL28666765 0.81 KMT2A (0.38) KMT2AMEN1ALDH1A1RECQLLMNA
SCHEMBL28373802 0.78 SLC18A3 (0.45) KMT2AMEN1ALDH1A1EPHX1RECQL
SCHEMBL28368681 0.78 SLC18A3 (0.45) KMT2AMEN1ALDH1A1EPHX1RECQL
SCHEMBL28368682 0.78 SLC18A3 (0.45) KMT2AMEN1ALDH1A1EPHX1RECQL
SCHEMBL28930446 0.77 KMT2A (0.36) KMT2AMEN1ALDH1A1HSD17B10LMNA
SCHEMBL21677891 0.75 CYP11B2 (0.36) ALDH1A1TRPA1
SCHEMBL27828506 0.73 KDM4E (0.47) KMT2AMEN1ALDH1A1EPHX1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997287-B Method for catalytic synthesis of 4-fluorotetrahydropyran derivative by taking tetrafluoroboric acid ionic liquid as fluorine source 陕西师范大学 2021-12-28 CN disclosed