Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776764 | 0.83 | GPR119 (0.69) | GPR119PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21607236 | 0.82 | GPR119 (0.48) | GPR119PIK3CDPDE4BPDE4APDE4C | |
| SCHEMBL21607019 | 0.80 | GPR119 (0.59) | GPR119PIK3CDPIK3CANPBWR1MCHR1 | |
| SCHEMBL23311676 | 0.79 | GPR119 (0.53) | GPR119PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29749146 | 0.79 | GPR119 (0.66) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20137646 | 0.79 | GPR119 (0.66) | GPR119NPBWR1MCHR1 | |
| SCHEMBL20070242 | 0.78 | PIK3CD (0.41) | PIK3CDPIK3CA | |
| SCHEMBL20137797 | 0.77 | GPR119 (0.67) | GPR119PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29686112 | 0.76 | GPR119 (0.60) | GPR119PIK3CDPIK3CAPDE4B | |
| SCHEMBL385907 | 0.76 | PIK3CD (0.51) | GPR119PIK3CDPIK3CACACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-B | Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2021-12-14 | — | — | CN | disclosed |