Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077283 | 0.90 | CHRM3 (0.40) | AOC3DYRK1APDE10AKDM4EMAP3K12 | |
| SCHEMBL24894887 | 0.81 | GRM2 (0.44) | AOC3DYRK1APDE10AKDM4EMAP3K12 | |
| SCHEMBL25195654 | 0.81 | GRM2 (0.44) | AOC3DYRK1APDE10AKDM4EMAP3K12 | |
| SCHEMBL24126987 | 0.81 | AOC3 (0.44) | AOC3DYRK1APDE10ADPP4DPP8 | |
| SCHEMBL21551344 | 0.78 | DPP4 (0.41) | AOC3DPP4DPP8DPP7KDM4E | |
| SCHEMBL19864978 | 0.77 | SMO (0.43) | AOC3KDM4ECYP2C19 | |
| SCHEMBL26077252 | 0.76 | ALDH1A1 (0.45) | AOC3KDM4ECYP2C19 | |
| SCHEMBL26077258 | 0.74 | ADRA1A (0.43) | KDM4E | |
| SCHEMBL24894892 | 0.74 | USP30 (0.36) | AOC3DYRK1APDE10AMAP3K12ACACB | |
| SCHEMBL23759883 | 0.74 | USP30 (0.36) | AOC3DYRK1APDE10AMAP3K12ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251166-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-109251166-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-01-22 | — | — | CN | disclosed |