Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261473 | 0.91 | LMNA (0.58) | LMNATSHRALDH1A1MAPTGAA | |
| SCHEMBL28655062 | 0.89 | SLC6A4 (0.58) | LMNATSHRSLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL28669916 | 0.87 | TSHR (0.51) | LMNATSHRALDH1A1MAPTGAA | |
| SCHEMBL28656051 | 0.87 | POLB (0.51) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL28665025 | 0.87 | LMNA (0.45) | LMNATSHRALDH1A1GAAKDM4E | |
| SCHEMBL28681880 | 0.85 | L3MBTL1 (0.48) | LMNATSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3230316 | 0.81 | TSHR (0.65) | LMNATSHRSLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL29500171 | 0.81 | TSHR (0.65) | LMNATSHRSLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL9356318 | 0.81 | KMT2A (0.47) | LMNASLC6A3SLC6A4MAPTGAA | |
| SCHEMBL9542216 | 0.81 | L3MBTL1 (0.46) | LMNASLC6A3SLC6A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020814-B | Polysubstituted 10-hydroxy phenanthrene and derivative thereof and synthesis method thereof | 南开大学 | 2021-06-29 | — | — | CN | disclosed |